A role for leukocyte integrins and extracellular matrix remodeling of adipose tissue in the risk of weight regain after weight loss
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چکیده
منابع مشابه
The role for adipose tissue in weight regain after weight loss
Weight regain after weight loss is a substantial challenge in obesity therapeutics. Dieting leads to significant adaptations in the homeostatic system that controls body weight, which promotes overeating and the relapse to obesity. In this review, we focus specifically on the adaptations in white adipose tissues that contribute to the biological drive to regain weight after weight loss. Weight ...
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15 صفحه اولWeight loss-induced stress in subcutaneous adipose tissue is related to weight regain.
Initial successful weight loss is often followed by weight regain after the dietary intervention. Compared with lean people, cellular stress in adipose tissue is increased in obese subjects. However, the relation between cellular stress and the risk for weight regain after weight loss is unclear. Therefore, we determined the expression levels of stress proteins during weight loss and weight mai...
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Exercise is a potent strategy to facilitate long-term weight maintenance. In addition to increasing energy expenditure and reducing appetite, exercise also favors the oxidation of dietary fat, which likely helps prevent weight re-gain. It is unclear whether this exercise-induced metabolic shift is due to changes in energy balance, or whether exercise imparts additional adaptations in the periph...
متن کاملThe defence of body weight: a physiological basis for weight regain after weight loss.
Although weight loss can usually be achieved by restricting food intake, the majority of dieters regain weight over the long-term. In the hypothalamus, hormonal signals from the gastrointestinal tract, adipose tissue and other peripheral sites are integrated to influence appetite and energy expenditure. Diet-induced weight loss is accompanied by several physiological changes which encourage wei...
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ژورنال
عنوان ژورنال: The American Journal of Clinical Nutrition
سال: 2017
ISSN: 0002-9165,1938-3207
DOI: 10.3945/ajcn.116.148874